CITI Training Practice Exam

ICH requires subjects to be informed about the lack of intended clinical benefit in the informed consent form (ICF). This is important because it promotes transparency and allows subjects to make an informed decision about participating in the study. Option B is incorrect because subjects should not only be informed about potential risks, but also any lack of intended benefit. Option C is incorrect because subjects have the right to know about the study's benefits and potential risks. Option D is incorrect because both the subjects and their legal representatives should be informed about the lack of intended clinical benefit.